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'Shadoo' prion sheds light on BSE

发布时间:2019-03-02 02:06:05来源:未知点击:

PRION diseases such as BSE and variant Creutzfeldt-Jakob disease (vCJD) just got more complicated. These diseases destroy the brain when a wrongly folded version of a prion protein called PrP begins converting normal PrP – which usually protects the brain – into the misfolded variety. Researchers had suspected that other types of prion might exist in the brain, but none had ever been identified – until now. Joel Watts from the University of Toronto in Canada and his colleagues have identified a prion in mouse brains that they call “Shadoo”,